A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19.

Autores

  • Ana Maria Marinho Andrade de Moura Prof. MSc. Universidade Federal do Rio Grande do Norte.
  • Anaís Concepción Marinho Andrade de Moura Discente de Medicina. Universidade Potiguar
  • DANY GERALDO kramer Prof. Dr. do Programa de Pós – Graduação em Saúde do Família do Nordeste – RENASF – Universidade Federal do Rio Grande do Norte http://orcid.org/0000-0001-7655-7444

DOI:

https://doi.org/10.17564/2316-3798.2020v8n2p272-280

Palavras-chave:

Remdesivir, Coronavirus, Therapy.

Resumo

Remdesivir (GS-5734) is a drug designed for application in patients with Ebola, being used in patients in the coronavirus outbreak in the Middle East. After internalization of the drug, at the cellular level, it is converted into its active form GS-441524, and binds viral RNA polymerase (RdRp) blocking viral replication. Thus, the present study aimed to discuss the potential use of Remdesivir in coronovavirus infections. Some observed studies report promising results in the recovery of critically ill patients with COVID 19, however, there are reports of serious adverse reactions, which led to the discontinuation of therapy with this drug. Thus, measuring the efficacy and safety of Remdesivir in the treatment of COVID 19 will require broader randomized, controlled and double-blind clinical trials, so that the data and scientific information generated can guide treatment protocols for this drug.

Biografia do Autor

Ana Maria Marinho Andrade de Moura, Prof. MSc. Universidade Federal do Rio Grande do Norte.

Prof. MSc. Universidade Federal do Rio Grande do Norte.

Anaís Concepción Marinho Andrade de Moura, Discente de Medicina. Universidade Potiguar

Discente de Medicina. Universidade Potiguar

DANY GERALDO kramer, Prof. Dr. do Programa de Pós – Graduação em Saúde do Família do Nordeste – RENASF – Universidade Federal do Rio Grande do Norte

Prof. Dr. do Programa de Pós – Graduação em Saúde do Família do Nordeste – RENASF – Universidade Federal do Rio Grande do Norte

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Publicado

2020-11-12

Como Citar

Andrade de Moura, A. M. M., Andrade de Moura, A. C. M., & kramer, D. G. (2020). A REVIEW ON THE USE OF REMDESIVIR IN THE CURRENT VIROSIS COVID-19. Interfaces Científicas - Saúde E Ambiente, 8(2), 272–280. https://doi.org/10.17564/2316-3798.2020v8n2p272-280

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